منابع مشابه
Overcoming inhibitions.
O rganophosphorus nerve agents and pesticides (Fig. 1) markedly increase the amount and duration of the action of acetylcholine at all of the synaptic sites where it acts, resulting in overstimulation of critical processes that can lead to incapacitation, muscle paralysis, and death. In a recent issue of PNAS, Albuquerque et al. (1) reported that a drug already in use for treating Alzheimer’s d...
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Dyneins are large minus-end-directed microtubule motors. Each dynein contains at least one dynein heavy chain (DHC) and a variable number of intermediate chains (IC), light intermediate chains (LIC) and light chains (LC). Here, we used genome sequence data from 24 diverse eukaryotes to assess the distribution of DHCs, ICs, LICs and LCs across Eukaryota. Phylogenetic inference identified nine DH...
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1. Chromatography on silica gel, combined with infrared spectrometry, has been used to analyse mixtures of bile acids. 2. The results obtained by applying this method to an ox bile-salt preparation are described. Methyl lithocholate (methyl 3-hydroxycholanate) (1.8 mg.), methyl deoxycholate (methyl 3:12-dihydroxycholanate) (38 mg.), methyl chenodeoxycholate (methyl 3:7-dihydroxycholanate) (0-6 ...
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Most evolutionary algorithms concerned with a memory of evolution aim at memorizing and reusing the recipes of past successes (e.g. fruitful operators or fruitful mutation directions). The scheme proposed here follows the opposite track, and memorizes the past failures of evolution (unnt oospring) through a virtual individual termed the virtual loser. The underlying metaphor is that oospring sh...
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We wish to thank Dr. Wilson for suggesting that the bilateral vocal cord paralysis we reported in a patient with Guillain Barre syndrome may have resulted from trauma secondary to intubation with a cuffinflated endotracheal tube. Although this explanation could have contributed to the paralysis, we believe it was primarily the result of the Guillain Barr6 syndrome because: 1. Prior to intubatio...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2015
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.2112iti2